In October, the weather in Thousand Oaks is typically warm. Average daily high temperature in October is about 23 degrees above zero. On average, Thousand Oaks has 21 sunny, 6 partly cloudy, 3 rainy, and 1 cloudy day in October. The rains are usually light. October as well as May, June, July, and August is considered the most comfortable time to visit Thousand Oaks.