January in South San Francisco is the rainiest, the cloudiest, and the coldest month of the year. In January, the weather in South San Francisco is typically warm. Average daily high temperature in January is about 13 degrees above zero. On average, South San Francisco has 11 rainy, 8 partly cloudy, 7 sunny, and 5 cloudy days in January. The rains are usually heavy. January as well as February, March, and December is considered the most uncomfortable time to visit South San Francisco.