October in Santo Domingo is the windiest month of the year. In October, the weather in Santo Domingo is typically hot. Average daily high temperature in October is about 28 degrees above zero. On average, Santo Domingo has 21 rainy, 8 cloudy, 1 sunny, and 1 partly cloudy day in October. The rains are usually heavy. October as well as January, February, March, and April is considered the most uncomfortable time to visit Santo Domingo.