In October, the weather in Santa Cruz del Quiché is typically warm. Average daily high temperature in October is about 21 degrees above zero. On average, Santa Cruz del Quiché has 24 rainy, 6 partly cloudy, and 1 sunny day in October. The rains are usually heavy. October as well as May, June, July, and August is considered the most uncomfortable time to visit Santa Cruz del Quiché.