January in Karpenisi is the rainiest, the cloudiest, and the coldest month of the year. In January, the weather in Karpenisi is typically cold. Average daily high temperature in January is about 5 degrees above zero. On average, Karpenisi has 21 rainy, 6 sunny, 2 cloudy, and 2 partly cloudy days in January. The rains are usually heavy. January as well as February, March, April, and November is considered the most uncomfortable time to visit Karpenisi.