In September, the weather in Karlovy Vary is typically warm. Average daily high temperature in September is about 16 degrees above zero. On average, Karlovy Vary has 12 rainy, 7 partly cloudy, 6 sunny, and 5 cloudy days in September. The rains are usually moderate. September as well as January, February, March, and April is considered the most uncomfortable time to visit Karlovy Vary.