October in São Tomé is the rainiest month of the year. In October, the weather in São Tomé is typically warm. Average daily high temperature in October is about 26 degrees above zero. On average, São Tomé has 25 rainy, 3 sunny, and 3 cloudy days in October. The rains are usually heavy. October as well as January, February, March, and April is considered the most uncomfortable time to visit São Tomé.