October in Puerto Ayora is the coldest month of the year. In October, the weather in Puerto Ayora is typically warm. Average daily high temperature in October is about 22 degrees above zero. On average, Puerto Ayora has 24 cloudy, 5 partly cloudy, and 2 sunny days in October. October as well as January, May, June, and July is considered the most comfortable time to visit Puerto Ayora.